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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:associatedWith
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gptkb:Charcot-Marie-Tooth_disease
gptkb:centronuclear_myopathy
epilepsy
optic atrophy
|
|
gptkbp:biologicalProcess
|
GTP binding
GTPase activity
|
|
gptkbp:cellularComponent
|
gptkb:Golgi_apparatus
gptkb:cytoplasm
gptkb:plasma_membrane
mitochondria
endosomes
|
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gptkbp:contains
|
gptkb:dynamin_1
gptkb:Drp1
gptkb:OPA1
GBPs
MxA
MxB
Vps1
atlastin
dynamin 2
dynamin 3
mitofusin
|
|
gptkbp:discoveredBy
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gptkb:James_E._Rothman
gptkb:Sandra_L._Schmid
|
|
gptkbp:domain
|
gptkb:pleckstrin_homology_domain
GTPase domain
GTPase effector domain
proline-rich domain
|
|
gptkbp:firstDescribed
|
1989
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:function
|
endocytosis
membrane remodeling
vesicle scission
|
|
gptkbp:GO_term
|
GO:0005525
GO:0007264
GO:0006886
GO:0006897
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dynamin family proteins
|
|
gptkbp:involves
|
mitochondrial fission
antiviral response
clathrin-mediated endocytosis
organelle division
|
|
gptkbp:orthologIn
|
C. elegans DRP-1
yeast Dnm1
|
|
gptkbp:regulates
|
vesicle trafficking
membrane fusion
membrane fission
synaptic vesicle recycling
|
|
gptkbp:bfsParent
|
gptkb:G1_motif
|
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gptkbp:bfsLayer
|
7
|