|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:discoveredBy
|
gptkb:Sandra_L._Schmid
|
|
gptkbp:domain
|
gptkb:pleckstrin_homology_domain
GTPase domain
proline-rich domain
|
|
gptkbp:firstDescribed
|
1989
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:function
|
endocytosis
membrane remodeling
vesicle scission
|
|
gptkbp:GO_term
|
GO:0005525
GO:0006886
|
|
gptkbp:hasMember
|
gptkb:MFN2
gptkb:DNM1
gptkb:DNM2
gptkb:DNM3
gptkb:MFN1
gptkb:OPA1
MxA
MxB
DRP1
GBP1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dynamin family
|
|
gptkbp:includes
|
gptkb:dynamin_1
gptkb:mitofusin_2
gptkb:Drp1
gptkb:OPA1
dynamin 2
dynamin 3
mitofusin 1
|
|
gptkbp:involves
|
mitochondrial fission
antiviral response
clathrin-mediated endocytosis
synaptic vesicle recycling
organelle division
|
|
gptkbp:mechanismOfAction
|
GTP hydrolysis
|
|
gptkbp:proteinFamily
|
guanine nucleotide exchange factor
|
|
gptkbp:relatedTo
|
mitochondrial dynamics
membrane fission
cellular trafficking
|
|
gptkbp:reviewedBy
|
gptkb:Nature_Reviews_Molecular_Cell_Biology
gptkb:Annual_Review_of_Cell_and_Developmental_Biology
|
|
gptkbp:structure
|
helical polymer
|
|
gptkbp:bfsParent
|
gptkb:DNM
gptkb:DNM2_gene
gptkb:DNM3_gene
|
|
gptkbp:bfsLayer
|
7
|