|
gptkbp:instanceOf
|
gptkb:chemical_compound
NMDA receptor antagonist
|
|
gptkbp:affects
|
glutamatergic neurotransmission
|
|
gptkbp:ATCCode
|
none
|
|
gptkbp:binds
|
gptkb:NMDA_receptor
|
|
gptkbp:CASNumber
|
77086-22-7
|
|
gptkbp:discoveredBy
|
gptkb:Merck
|
|
gptkbp:drugClass
|
dissociative anesthetic
|
|
gptkbp:effect
|
neuroprotective
anticonvulsant
psychotomimetic
|
|
gptkbp:hasInChIKey
|
YQEZLKZALYSWHR-VIFPVBQESA-N
|
|
gptkbp:hasMolecularFormula
|
C16H15N
|
|
gptkbp:hasSMILES
|
CC1C2=CC=CC=C2C(C3=CC=CC=C13)N
|
|
gptkbp:hasUNII
|
J1DOI7UV76
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dizocilpine
|
|
gptkbp:isNotApprovedFor
|
human use
|
|
gptkbp:isStructurallyRelatedTo
|
phencyclidine (PCP)
|
|
gptkbp:IUPACName
|
(5S,10R)-(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine
|
|
gptkbp:legalStatus
|
uncontrolled (most countries)
|
|
gptkbp:molecularWeight
|
221.295 g/mol
|
|
gptkbp:PubChem_CID
|
3035
CHEMBL39133
|
|
gptkbp:routeOfAdministration
|
experimental (animal studies)
|
|
gptkbp:synonym
|
MK-801
dizocilpine maleate
|
|
gptkbp:usedInResearchOn
|
epilepsy
schizophrenia
neuroprotection
|
|
gptkbp:bfsParent
|
gptkb:Phencyclidine
gptkb:NMDA_receptor
gptkb:NMDA_receptors
|
|
gptkbp:bfsLayer
|
7
|