|
gptkbp:instanceOf
|
gptkb:chemical_compound
environmental pollutant
|
|
gptkbp:affects
|
development
endocrine system
immune system
reproductive system
|
|
gptkbp:appearance
|
colorless solid
|
|
gptkbp:bioaccumulation
|
yes
|
|
gptkbp:carcinogenicity
|
gptkb:Group_1_(IARC)
|
|
gptkbp:CASNumber
|
1746-01-6
|
|
gptkbp:category
|
endocrine disruptor
halogenated aromatic hydrocarbon
organochloride
persistent organic pollutant
toxicant
|
|
gptkbp:chemicalFormula
|
C12H4Cl4O2
|
|
gptkbp:discoveredBy
|
1957
|
|
gptkbp:environmental_persistence
|
very persistent
|
|
gptkbp:foundIn
|
herbicide manufacturing
paper bleaching
waste incineration
|
|
gptkbp:half-life_in_humans
|
7 to 11 years
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dioxin (TCDD)
|
|
gptkbp:IUPACName
|
gptkb:2,3,7,8-tetrachlorodibenzo-p-dioxin
|
|
gptkbp:main_metabolite
|
gptkb:hydroxylated_TCDD
|
|
gptkbp:main_target_organ
|
gptkb:skin
liver
immune system
|
|
gptkbp:mechanism_of_toxicity
|
binds to aryl hydrocarbon receptor (AhR)
|
|
gptkbp:meltingPoint
|
305 °C
|
|
gptkbp:molecularWeight
|
321.97 g/mol
|
|
gptkbp:producedBy
|
combustion
industrial processes
|
|
gptkbp:regulates
|
gptkb:WHO
gptkb:US_EPA
|
|
gptkbp:relatedTo
|
gptkb:cancer
gptkb:chloracne
birth defects
|
|
gptkbp:routeOfExposure
|
gptkb:food
air
soil
|
|
gptkbp:solubility
|
insoluble
|
|
gptkbp:synonym
|
gptkb:2,3,7,8-TCDD
gptkb:tetrachlorodibenzo-p-dioxin
gptkb:TCDD
|
|
gptkbp:toxicity
|
highly toxic
|
|
gptkbp:UNNumber
|
gptkb:UN_3465
|
|
gptkbp:used_in
|
gptkb:Agent_Orange
|
|
gptkbp:bfsParent
|
gptkb:Agent_Orange
|
|
gptkbp:bfsLayer
|
6
|