Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:appearance |
white crystalline solid
|
| gptkbp:CASNumber |
79-43-6
|
| gptkbp:category |
gptkb:organochlorides
acetic acids halogenated carboxylic acids |
| gptkbp:chemicalFormula |
C2H2Cl2O2
|
| gptkbp:effect |
shifts metabolism from glycolysis to glucose oxidation
activates pyruvate dehydrogenase |
| https://www.w3.org/2000/01/rdf-schema#label |
dichloroacetate
|
| gptkbp:IUPACName |
dichloroacetic acid
|
| gptkbp:mechanismOfAction |
inhibits pyruvate dehydrogenase kinase
|
| gptkbp:molecularWeight |
128.94 g/mol
|
| gptkbp:pKa |
1.35
|
| gptkbp:relatedTo |
chloroacetic acid
trichloroacetic acid |
| gptkbp:solubility |
soluble
|
| gptkbp:toxicity |
can cause peripheral neuropathy
|
| gptkbp:uses |
research chemical
potential cancer therapy |
| gptkbp:bfsParent |
gptkb:PDK2
|
| gptkbp:bfsLayer |
7
|