daunomycin

URI: https://gptkb.org/entity/daunomycin
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:antineoplastic_agent
gptkb:anthracycline_antibiotic
gptkbp:administeredBy intravenous injection
gptkbp:ATCCode L01DB02
gptkbp:CASNumber 20830-81-3
gptkbp:chemicalFormula C27H29NO10
gptkbp:color red
gptkbp:derivedFrom gptkb:Streptomyces_peucetius
gptkbp:discoveredBy gptkb:Federico_Arcamone
gptkbp:discoveredIn 1963
gptkbp:drugClass antineoplastic agents
gptkbp:excretion urine
bile
gptkbp:hasUNII 80168379AG
gptkbp:IUPACName (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(hydroxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione
gptkbp:listedOn gptkb:WHO_Model_List_of_Essential_Medicines
gptkbp:mechanismOfAction DNA intercalation
topoisomerase II inhibition
gptkbp:metabolism liver
gptkbp:molecularWeight 527.52 g/mol
gptkbp:PubChem_CID 30323
CHEBI:28497
DB00694
gptkbp:sideEffect nausea
hair loss
cardiotoxicity
myelosuppression
gptkbp:synonym gptkb:daunorubicin
gptkbp:usedFor treatment of acute lymphoblastic leukemia
treatment of acute myeloid leukemia
gptkbp:bfsParent gptkb:daunorubicin
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label daunomycin