cutaneous SCC

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:affects gptkb:skin
gptkbp:canBe invasive
locally aggressive
in situ (Bowen's disease)
gptkbp:canMetastasizeTo lymph nodes
distant organs
gptkbp:cause chronic inflammation
arsenic exposure
genetic disorders (e.g., xeroderma pigmentosum)
gptkbp:commonIn elderly
fair-skinned individuals
gptkbp:diagnosedBy biopsy
gptkbp:firstDescribed 19th century
gptkbp:fullName gptkb:cutaneous_squamous_cell_carcinoma
https://www.w3.org/2000/01/rdf-schema#label cutaneous SCC
gptkbp:ICD-10_code C44
gptkbp:incidence increasing worldwide
gptkbp:morphologicalType atypical squamous cells
keratin pearls
gptkbp:mortalityRate low if treated early
gptkbp:occurredIn ears
legs
scalp
hands
lips
genitalia
sun-exposed areas
gptkbp:originatedIn gptkb:keratinocytes
gptkbp:prevention sun protection
avoiding tanning beds
regular skin checks
gptkbp:prognosis generally good if detected early
gptkbp:recurrence yes
gptkbp:relatedTo melanoma
basal cell carcinoma
gptkbp:riskFactor radiation therapy
immunosuppression
human papillomavirus infection
chronic wounds
gptkbp:symptom ulceration
skin lesion
non-healing sore
scaly patch
gptkbp:treatment gptkb:Mohs_surgery
radiation therapy
surgical excision
topical chemotherapy
gptkbp:bfsParent gptkb:Cutaneous_Squamous_Cell_Carcinoma
gptkbp:bfsLayer 5