Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
complement system component |
| gptkbp:activatedBy |
gptkb:lectin_pathway
alternative pathway classical pathway |
| gptkbp:deficiencyCauses |
increased susceptibility to bacterial infections
|
| gptkbp:discoveredBy |
gptkb:Jules_Bordet
|
| gptkbp:discoveredIn |
1895
|
| gptkbp:encodedBy |
C3 gene
|
| gptkbp:foundIn |
gptkb:human
other mammals |
| gptkbp:function |
inflammation
immune response opsonization lysis of pathogens |
| https://www.w3.org/2000/01/rdf-schema#label |
complement component 3 (C3)
|
| gptkbp:locatedOnChromosome |
gptkb:19p13.3
|
| gptkbp:location |
blood plasma
|
| gptkbp:molecularWeight |
~185 kDa
|
| gptkbp:OMIM |
120700
|
| gptkbp:predecessor |
gptkb:C3b
C3a |
| gptkbp:relatedTo |
complement component 4 (C4)
complement component 5 (C5) |
| gptkbp:structure |
gptkb:protein
|
| gptkbp:subunit |
complement system
|
| gptkbp:UniProtID |
P01024
|
| gptkbp:bfsParent |
gptkb:Pegcetacoplan
gptkb:C3d gptkb:C3dg |
| gptkbp:bfsLayer |
8
|