|
gptkbp:instanceOf
|
gptkb:drug
selective estrogen receptor modulator
|
|
gptkbp:approvedBy
|
1967
|
|
gptkbp:ATCCode
|
G03GB02
|
|
gptkbp:bioavailability
|
well absorbed
|
|
gptkbp:brand
|
Clomid
Serophene
|
|
gptkbp:CASNumber
|
911-45-5
|
|
gptkbp:category
|
fertility medication
hormonal agent
|
|
gptkbp:chemicalFormula
|
C26H28ClNO
|
|
gptkbp:contraindication
|
gptkb:liver_disease
gptkb:ovarian_cysts
pregnancy
unexplained uterine bleeding
|
|
gptkbp:discoveredBy
|
gptkb:William_H._Allen
|
|
gptkbp:eliminationHalfLife
|
5-7 days
|
|
gptkbp:excretion
|
urine
feces
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
clomifene
|
|
gptkbp:legalStatus
|
prescription only
Rx-only
|
|
gptkbp:legalStatusAU
|
S4 (Prescription only)
|
|
gptkbp:legalStatusUK
|
POM
|
|
gptkbp:mechanismOfAction
|
estrogen receptor antagonist in hypothalamus
|
|
gptkbp:MedlinePlusID
|
a682704
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
405.96 g/mol
|
|
gptkbp:pregnancyCategory
|
D
X
X (contraindicated)
|
|
gptkbp:proteinBinding
|
high
|
|
gptkbp:PubChem_CID
|
2800
DB00882
CHEMBL83
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
abdominal discomfort
hot flashes
visual disturbances
ovarian enlargement
|
|
gptkbp:synonym
|
gptkb:clomiphene
|
|
gptkbp:UNII
|
1UVS4V6Z4Y
|
|
gptkbp:usedFor
|
ovulation induction
infertility treatment
|
|
gptkbp:bfsParent
|
gptkb:G02BA03
|
|
gptkbp:bfsLayer
|
7
|