clear cell carcinoma of the endometrium

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:frequency rare
<5% of endometrial carcinomas
gptkbp:hasGeneticAlteration ARID1A mutation
PIK3CA mutation
gptkbp:hasHistologicalFeature clear cytoplasm
hobnail cells
papillary or tubulocystic architecture
gptkbp:hasICD-O-3Code 8310/3
gptkbp:hasImmunohistochemicalMarker gptkb:Napsin_A
gptkb:HNF-1β
p53 (abnormal in some cases)
gptkbp:hasMalignantCellType clear cell epithelial cell
gptkbp:hasMetastasisSite lungs
liver
lymph nodes
peritoneum
gptkbp:hasPrimarySite gptkb:endometrium
https://www.w3.org/2000/01/rdf-schema#label clear cell carcinoma of the endometrium
gptkbp:medianAge 60s-70s
gptkbp:prognosis stage at diagnosis
generally poor
lymphovascular invasion
myometrial invasion
gptkbp:riskFactor advanced age
history of endometrial hyperplasia
gptkbp:stageName gptkb:FIGO
gptkbp:subspecies uterine cancer
gynecologic cancer
gptkbp:treatment surgery
radiation therapy
chemotherapy
gptkbp:bfsParent gptkb:cancer
gptkbp:bfsLayer 4