chronic Hepatitis C

GPTKB entity

Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:disease
chronic viral infection
gptkbp:affects liver
gptkbp:canBeAsymptomatic true
gptkbp:canBeCured true
gptkbp:cause cirrhosis
hepatocellular carcinoma
extrahepatic manifestations
gptkbp:causedBy gptkb:Hepatitis_C_virus
gptkbp:complication gptkb:hepatic_encephalopathy
liver failure
portal hypertension
gptkbp:cureRateWithDAA over 95%
gptkbp:diagnosedBy HCV RNA test
HCV antibody test
gptkbp:extrahepaticManifestation leukemia
nephrotic syndrome
cryoglobulinemia
gptkbp:firstDescribed 1989
https://www.w3.org/2000/01/rdf-schema#label chronic Hepatitis C
gptkbp:ICD-10_code B18.2
gptkbp:noVaccine true
gptkbp:prevalence over 70 million people worldwide
gptkbp:prevention screening blood products
avoid sharing needles
gptkbp:progression may take decades
gptkbp:riskFactor HIV infection
hemodialysis
tattooing with unsterile equipment
injection drug use
gptkbp:screeningRecommendedFor high-risk populations
people born 1945-1965 (US)
gptkbp:symptom nausea
abdominal pain
fatigue
jaundice
joint pain
gptkbp:transmittedBy blood-to-blood contact
sharing needles
blood transfusion (before 1992)
gptkbp:treatment direct-acting antivirals
interferon (historically)
ribavirin (historically)
gptkbp:bfsParent gptkb:Hepatitis_C
gptkbp:bfsLayer 5