Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
nonsteroidal anti-inflammatory drug |
| gptkbp:approvalYear |
1996 (for veterinary use in US)
|
| gptkbp:ATCCode |
QM01AE91
|
| gptkbp:brand |
gptkb:Rimadyl
Novox Vetprofen |
| gptkbp:CASNumber |
53716-49-7
|
| gptkbp:chemicalClass |
propionic acid derivative
|
| gptkbp:compatibleWith |
human use in the United States
|
| gptkbp:contraindication |
pre-existing kidney disease
pre-existing liver disease use with corticosteroids use with other NSAIDs |
| gptkbp:discoveredBy |
gptkb:Pfizer
|
| gptkbp:eliminationHalfLife |
8 hours (dogs)
|
| gptkbp:excretion |
kidneys
|
| gptkbp:hasMolecularFormula |
C15H12ClNO2
|
| https://www.w3.org/2000/01/rdf-schema#label |
carprofen
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
COX inhibitor
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
not established in animals
|
| gptkbp:routeOfAdministration |
oral
injectable |
| gptkbp:sideEffect |
liver toxicity
gastrointestinal upset kidney toxicity |
| gptkbp:species |
gptkb:dog
cats (limited, off-label) horses (limited, off-label) |
| gptkbp:synonym |
(±)-6-chloro-α-methylcarbazole-2-acetic acid
|
| gptkbp:usedFor |
inflammation reduction in animals
pain relief in animals osteoarthritis in dogs postoperative pain in dogs |
| gptkbp:bfsParent |
gptkb:Rimadyl
gptkb:Carprieve |
| gptkbp:bfsLayer |
8
|