Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
calcium ions
|
| gptkbp:alternativeName |
gptkb:CANP
gptkb:EC_3.4.22.17 calcium-activated neutral protease |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
muscular dystrophy cataract formation ischemic injury |
| gptkbp:discoveredBy |
gptkb:David_E._G._Green
|
| gptkbp:discoveredIn |
1964
|
| gptkbp:domain |
gptkb:EF-hand_domain
C2-like domain protease core domain |
| gptkbp:EC_number |
3.4.22.17
|
| gptkbp:foundIn |
animals
fungi plants some bacteria |
| gptkbp:function |
calcium-dependent cysteine protease
|
| https://www.w3.org/2000/01/rdf-schema#label |
calpain
|
| gptkbp:inhibitedBy |
gptkb:calpastatin
|
| gptkbp:proteinFamily |
gptkb:CAPN
|
| gptkbp:relatedTo |
apoptosis
signal transduction cell motility muscle protein degradation cytoskeletal remodeling |
| gptkbp:structure |
papain-like fold
|
| gptkbp:subunit |
large catalytic subunit
small regulatory subunit |
| gptkbp:bfsParent |
gptkb:calpastatin
|
| gptkbp:bfsLayer |
6
|