Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
ion channel
|
| gptkbp:blockedIn |
gptkb:nifedipine
gptkb:verapamil diltiazem |
| gptkbp:dysregulationAssociatedWith |
gptkb:arrhythmia
epilepsy migraine |
| gptkbp:encodedBy |
CACNA1C gene (L-type)
CACNA1H gene (T-type) |
| gptkbp:foundIn |
gptkb:plasma_membrane
endoplasmic reticulum membrane sarcoplasmic reticulum membrane |
| gptkbp:function |
allow passage of Ca2+ ions across cell membranes
|
| https://www.w3.org/2000/01/rdf-schema#label |
calcium ion channels
|
| gptkbp:involvedIn |
gene expression
cell signaling muscle contraction neurotransmitter release |
| gptkbp:regulates |
intracellular calcium concentration
|
| gptkbp:subclassOf |
gptkb:ligand-gated_ion_channels
voltage-gated ion channels |
| gptkbp:type |
L-type calcium channel
N-type calcium channel P/Q-type calcium channel R-type calcium channel T-type calcium channel |
| gptkbp:bfsParent |
gptkb:cAMP
|
| gptkbp:bfsLayer |
7
|