|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
7
|
|
gptkbp:bfsParent
|
gptkb:dihydroartemisinin
|
|
gptkbp:activities
|
artemisinin derivative
|
|
gptkbp:appointed_by
|
oral tablet
|
|
gptkbp:approves
|
gptkb:2001
gptkb:World_Health_Organization
|
|
gptkbp:availability
|
widely available
|
|
gptkbp:can_be_used_with
|
gptkb:artemether
gptkb:lumefantrine
|
|
gptkbp:clinical_trial
|
ongoing
malaria caused by Plasmodium falciparum
|
|
gptkbp:contraindication
|
severe liver disease
severe heart conditions
|
|
gptkbp:developed_by
|
gptkb:Novartis
|
|
gptkbp:dosage_form
|
tablets
based on body weight
120 mg lumefantrine
20 mg artemether
|
|
gptkbp:duration
|
3 days
|
|
gptkbp:formulation
|
fixed-dose combination
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
artemether-lumefantrine
|
|
gptkbp:interacts_with
|
certain antifungals
certain antiretrovirals
|
|
gptkbp:invention
|
patented
|
|
gptkbp:is_available_in
|
many countries
|
|
gptkbp:is_effective_against
|
viral infections
bacterial infections
|
|
gptkbp:is_monitored_by
|
recommended during treatment
|
|
gptkbp:is_used_for
|
treatment of malaria
|
|
gptkbp:lifespan
|
2.5 hours
3-6 hours for lumefantrine
|
|
gptkbp:marketed_as
|
gptkb:Coartem
|
|
gptkbp:pharmacokinetics
|
high bioavailability
rapid absorption
|
|
gptkbp:previous_name
|
gptkb:battle
|
|
gptkbp:price
|
varies by country
|
|
gptkbp:requires
|
available online
|
|
gptkbp:shelf_life
|
2 years
|
|
gptkbp:side_effect
|
dizziness
headache
nausea
|
|
gptkbp:storage
|
store at room temperature
|
|
gptkbp:suitable_for
|
gptkb:WHO
breastfeeding women
pregnant women in first trimester
|
|
gptkbp:used_in
|
combination therapy
|
|
gptkbp:water_resistance
|
low resistance reported
|