antimycin A

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkb:antibiotic
herbicide
gptkbp:CASNumber 1397-94-0
gptkbp:category lactone
antifungal agent
respiratory chain inhibitor
gptkbp:chemicalFormula C28H40N2O9
gptkbp:discoveredBy S. A. Waksmann
gptkbp:discoveredIn 1940s
https://www.w3.org/2000/01/rdf-schema#label antimycin A
gptkbp:inhibitedBy complex III (cytochrome bc1 complex)
gptkbp:IUPACName (2R,3S,4S,6R,7S,8R,9S,10R,11R,12S,13R,14S,15R,16R)-8-[(2R,3S,4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-15,16-diol
gptkbp:mechanismOfAction inhibits mitochondrial electron transport chain
gptkbp:molecularWeight 548.62 g/mol
gptkbp:producedBy gptkb:Streptomyces_bacteria
gptkbp:solubility slightly soluble in water
soluble in ethanol
gptkbp:toxicity toxic to fish
toxic to aquatic invertebrates
toxic to mammals at high doses
gptkbp:usedAs piscicide
research tool in biochemistry
gptkbp:bfsParent gptkb:cytochrome_bc1_complex
gptkbp:bfsLayer 7