antimycin A

URI: https://gptkb.org/entity/antimycin_A

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:chemical_compound gptkb:antibiotic gptkb:herbicide
gptkbp:CASNumber	1397-94-0
gptkbp:category	gptkb:antifungal_agent gptkb:lactone respiratory chain inhibitor
gptkbp:chemicalFormula	C28H40N2O9
gptkbp:discoveredBy	S. A. Waksmann
gptkbp:discoveredIn	1940s
gptkbp:inhibitedBy	complex III (cytochrome bc1 complex)
gptkbp:IUPACName	(2R,3S,4S,6R,7S,8R,9S,10R,11R,12S,13R,14S,15R,16R)-8-[(2R,3S,4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-15,16-diol
gptkbp:mechanismOfAction	inhibits mitochondrial electron transport chain
gptkbp:molecularWeight	548.62 g/mol
gptkbp:producedBy	gptkb:Streptomyces_bacteria
gptkbp:solubility	slightly soluble in water soluble in ethanol
gptkbp:toxicity	toxic to fish toxic to aquatic invertebrates toxic to mammals at high doses
gptkbp:usedAs	gptkb:piscicide research tool in biochemistry
gptkbp:bfsParent	gptkb:cytochrome_bc1_complex gptkb:complex_III gptkb:mitochondrial_respiratory_chain_complex_III gptkb:ubiquinol-cytochrome_c_reductase_complex gptkb:Electron_Transport_Chain
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	antimycin A