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gptkbp:instance_of
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gptkb:neurodegenerative_diseases
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|
gptkbp:affects
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motor neurons
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|
gptkbp:cause
|
death of motor neurons
|
|
gptkbp:clinical_trial
|
ongoing
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gptkbp:condition
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gptkb:frontotemporal_dementia
pain
spasticity
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gptkbp:diagnosis
|
clinical examination
varies by individual
electromyography
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gptkbp:environmental_concerns
|
smoking
exposure to toxins
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gptkbp:famous_person
|
gptkb:Jason_Becker
gptkb:A._J._Styles
gptkb:Pat_Quinn
gptkb:Steve_Gleason
gptkb:Stephen_Hawking
gptkb:Timothy_Green
gptkb:Morrissey
gptkb:Lou_Gehrig
gptkb:David_Niven
Glen Mc Mahon
|
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gptkbp:first_described_by
|
gptkb:Jean-Martin_Charcot
|
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gptkbp:genetic_studies
|
C9orf72 mutations
SOD1 mutations
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
amyotrophic lateral sclerosis
|
|
gptkbp:is_involved_in
|
gptkb:ALS_Therapy_Development_Institute
gptkb:ALS_Association
gptkb:MDA_(Muscular_Dystrophy_Association)
|
|
gptkbp:known_as
|
gptkb:Lou_Gehrig's_disease
|
|
gptkbp:premiered_on
|
typically between ages 40 and 70
|
|
gptkbp:prevalence
|
2 per 100,000 people
|
|
gptkbp:research
|
ongoing studies
|
|
gptkbp:symptoms
|
respiratory failure
difficulty speaking
muscle weakness
difficulty swallowing
muscle atrophy
|
|
gptkbp:treatment
|
gptkb:riluzole
gptkb:edaravone
supportive care
|
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gptkbp:bfsParent
|
gptkb:Stephen_Hawking
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gptkbp:bfsLayer
|
3
|