Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Cardiology
|
| gptkbp:approves |
gptkb:1985
|
| gptkbp:atccode |
C01 BD01
|
| gptkbp:available_in |
gptkb:Australia
gptkb:Canada gptkb:United_Kingdom gptkb:United_States |
| gptkbp:available_on |
gptkb:tablet
injection |
| gptkbp:brand |
gptkb:Cordarone
gptkb:Pacerone |
| gptkbp:casnumber |
81161-70-0
|
| gptkbp:chemical_formula |
C25 H29 I2 N
|
| gptkbp:contraindication |
hypersensitivity to amiodarone
second or third degree AV block severe sinus node dysfunction |
| gptkbp:financials |
DB00529
|
| https://www.w3.org/2000/01/rdf-schema#label |
amiodarone
|
| gptkbp:interacts_with |
gptkb:fruit
gptkb:digoxin gptkb:warfarin statins |
| gptkbp:is_part_of |
antiarrhythmic therapy
|
| gptkbp:is_used_by |
cardiologists
emergency medicine physicians hospital pharmacists |
| gptkbp:lifespan |
15 to 100 days
|
| gptkbp:mechanism_of_action |
blocks sodium channels
blocks calcium channels blocks potassium channels |
| gptkbp:metabolism |
hepatic
|
| gptkbp:route_of_administration |
oral
intravenous |
| gptkbp:side_effect |
liver toxicity
thyroid dysfunction skin discoloration pulmonary toxicity |
| gptkbp:suitable_for |
pregnant women
nursing mothers patients with severe liver disease patients with severe lung disease patients with thyroid disease |
| gptkbp:used_for |
treatment of atrial fibrillation
treatment of atrial flutter treatment of ventricular tachycardia |
| gptkbp:bfsParent |
gptkb:Sovaldi
gptkb:ledipasvir gptkb:velpatasvir |
| gptkbp:bfsLayer |
5
|