Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
|
| gptkbp:antidote |
no specific antidote
|
| gptkbp:category |
mycotoxin
hepatotoxin |
| gptkbp:chemicalClass |
peptide
|
| gptkbp:discoveredBy |
Heinrich O. Wieland
|
| gptkbp:firstIsolatedFrom |
1941
|
| gptkbp:foundIn |
gptkb:Amanita_bisporigera
gptkb:Amanita_phalloides gptkb:Amanita_virosa |
| gptkbp:hasMolecularFormula |
C39H54N10O14
|
| https://www.w3.org/2000/01/rdf-schema#label |
amanitin
|
| gptkbp:LD50 |
0.1 mg/kg (mouse, intravenous)
|
| gptkbp:mechanismOfAction |
inhibits RNA polymerase II
|
| gptkbp:subspecies |
gptkb:alpha-amanitin
gptkb:beta-amanitin gptkb:gamma-amanitin epsilon-amanitin |
| gptkbp:toxicity |
kidney failure
liver failure |
| gptkbp:treatment |
supportive care
|
| gptkbp:bfsParent |
gptkb:alpha-amanitin
gptkb:phallotoxin |
| gptkbp:bfsLayer |
6
|