Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
gptkb:protein |
| gptkbp:alternativeName |
gptkb:alpha-toxin
|
| gptkbp:discoveredBy |
Frederick Loeffler
|
| gptkbp:discoveredIn |
1887
|
| gptkbp:effect |
causes cell lysis
|
| gptkbp:function |
forms pores in cell membranes
|
| gptkbp:gene |
hla
|
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-hemolysin
|
| gptkbp:mechanismOfAction |
binds to cell membrane and oligomerizes
forms transmembrane pores |
| gptkbp:molecularWeight |
33 kDa
|
| gptkbp:pathogenicRole |
contributes to virulence of S. aureus
|
| gptkbp:PDB |
7AHL
|
| gptkbp:producedBy |
gptkb:Staphylococcus_aureus
|
| gptkbp:structure |
heptameric pore-forming complex
|
| gptkbp:target |
gptkb:leukocytes
platelets erythrocytes |
| gptkbp:usedIn |
biotechnology research
membrane studies |
| gptkbp:bfsParent |
gptkb:alpha-toxin
|
| gptkbp:bfsLayer |
7
|