alfacalcidol

URI: https://gptkb.org/entity/alfacalcidol
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkb:vitamin_D_analog
gptkbp:approvedBy 1978
gptkbp:ATCCode A11CC03
gptkbp:brand Alfa D
Alfacalcidol Teva
Alpha D3
Alphadol
One-Alpha
gptkbp:CASNumber 41294-56-8
gptkbp:chemicalClass secosteroid
gptkbp:contraindication gptkb:hypercalcemia
vitamin D toxicity
gptkbp:developedBy Leo Pharmaceutical Products
gptkbp:eliminationHalfLife 3 hours
gptkbp:hasMolecularFormula C27H44O2
https://www.w3.org/2000/01/rdf-schema#label alfacalcidol
gptkbp:IUPACName (5Z,7E,22E)-(1R,3aS,7aR,9aR,10aS,12aS)-1,3a,7a,9a,10a,12a-hexamethyl-4,5,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-1-ol
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction increases intestinal absorption of calcium and phosphate
modulates bone mineralization
gptkbp:metabolism gptkb:calcitriol
gptkbp:pregnancyCategory gptkb:C_(Australia)
C (US)
gptkbp:PubChem_CID gptkb:CHEMBL1201197
5282180
DB01436
gptkbp:routeOfAdministration oral
intravenous
gptkbp:sideEffect gptkb:hypercalcemia
nausea
vomiting
headache
pruritus
rash
hyperphosphatemia
gptkbp:synonym 1α-hydroxyvitamin D3
gptkbp:UNII H6892V57JW
gptkbp:usedFor gptkb:bone
gptkb:osteomalacia
gptkb:rickets
hypocalcemia
renal osteodystrophy
gptkbp:bfsParent gptkb:calcitriol
gptkbp:bfsLayer 5