Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:ALDOA
|
| gptkbp:cofactor |
none required
|
| gptkbp:discoveredBy |
1940s
|
| gptkbp:EC_number |
4.1.2.13
|
| gptkbp:encodedBy |
ALDOA gene
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
developing embryo adult brain |
| gptkbp:function |
catalyzes the reversible cleavage of fructose-1,6-bisphosphate
|
| https://www.w3.org/2000/01/rdf-schema#label |
aldolase A, muscle
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_16
16q22.2 |
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
39 kDa
|
| gptkbp:pathway |
glycolysis
|
| gptkbp:product |
gptkb:glyceraldehyde_3-phosphate
dihydroxyacetone phosphate |
| gptkbp:significance |
mutations cause glycogen storage disease type XII
|
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
fructose-1,6-bisphosphate
|
| gptkbp:tissue_specificity |
gptkb:skeletal_muscle
brain erythrocytes |
| gptkbp:bfsParent |
gptkb:ALDOA
|
| gptkbp:bfsLayer |
7
|