|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:fructose-bisphosphate_aldolase_A
gptkb:muscle-type_aldolase
|
|
gptkbp:catalyzes
|
fructose-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate
|
|
gptkbp:cofactor
|
none
|
|
gptkbp:deficiencyCauses
|
gptkb:hereditary_fructose_intolerance
|
|
gptkbp:discoveredBy
|
gptkb:Carl_Neuberg
|
|
gptkbp:discoveredIn
|
1918
|
|
gptkbp:EC_number
|
4.1.2.13
|
|
gptkbp:enzymeClassification
|
lyase
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
fetal tissues
brain (low levels)
heart (low levels)
kidney (low levels)
liver (low levels)
lung (low levels)
|
|
gptkbp:family
|
gptkb:aldolase_family
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
brain
erythrocytes
|
|
gptkbp:gene
|
gptkb:ALDOA
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
aldolase A
|
|
gptkbp:involves
|
glycolysis
gluconeogenesis
|
|
gptkbp:locatedOnChromosome
|
16q22.2
|
|
gptkbp:molecularWeight
|
39 kDa
|
|
gptkbp:OMIM
|
103850
|
|
gptkbp:PDB
|
gptkb:4ALD
|
|
gptkbp:product
|
gptkb:glyceraldehyde_3-phosphate
dihydroxyacetone phosphate
|
|
gptkbp:structure
|
homotetramer
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
|
|
gptkbp:substrate
|
gptkb:fructose_1,6-bisphosphate
|
|
gptkbp:UniProtID
|
P04075
|
|
gptkbp:bfsParent
|
gptkb:aldolase
gptkb:ALDOA
|
|
gptkbp:bfsLayer
|
7
|