acute graft versus host disease
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
|
| gptkbp:affects |
patients after allogeneic hematopoietic stem cell transplantation
|
| gptkbp:alsoKnownAs |
acute GVHD
|
| gptkbp:cause |
gptkb:chronic_graft_versus_host_disease
|
| gptkbp:causedBy |
donor immune cells attacking recipient tissues
|
| gptkbp:complication |
allogeneic bone marrow transplantation
|
| gptkbp:diagnosedBy |
clinical criteria
biopsy |
| https://www.w3.org/2000/01/rdf-schema#label |
acute graft versus host disease
|
| gptkbp:ICD-10_code |
T86.0
|
| gptkbp:MeSH_ID |
D016104
|
| gptkbp:mortalityRate |
high in severe cases
|
| gptkbp:onset |
within 100 days after transplantation
|
| gptkbp:prevention |
immunosuppressive prophylaxis
|
| gptkbp:riskFactor |
gptkb:HLA_mismatch
older age of recipient unrelated donor |
| gptkbp:stageName |
grade I
grade II grade III grade IV |
| gptkbp:symptom |
skin rash
liver dysfunction gastrointestinal symptoms |
| gptkbp:treatment |
corticosteroids
immunosuppressive agents |
| gptkbp:bfsParent |
gptkb:Mesoblast_Limited
gptkb:chronic_graft_versus_host_disease |
| gptkbp:bfsLayer |
8
|