Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
small molecule |
gptkbp:approvedBy |
gptkb:European_Union
gptkb:United_States |
gptkbp:ATCCode |
D11AH10
|
gptkbp:brand |
Cibinqo
|
gptkbp:CASNumber |
1184570-46-8
|
gptkbp:developedBy |
gptkb:Pfizer
|
gptkbp:eliminationHalfLife |
5 hours
|
gptkbp:hasMolecularFormula |
C21H21F3N6O2
|
https://www.w3.org/2000/01/rdf-schema#label |
abrocitinib
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
Janus kinase 1 inhibitor
|
gptkbp:metabolism |
liver
|
gptkbp:pregnancyCategory |
not recommended
|
gptkbp:proteinBinding |
64%
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
nausea
headache upper respiratory tract infection herpes simplex infection |
gptkbp:usedFor |
gptkb:atopic_dermatitis
|
gptkbp:bfsParent |
gptkb:Janus_kinases
|
gptkbp:bfsLayer |
8
|