Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
selective estrogen receptor modulator |
| gptkbp:CASNumber |
119718-57-5
|
| gptkbp:chemicalFormula |
C25H27NO2
|
| gptkbp:clinicalTrialPhase |
Phase III
|
| gptkbp:developedBy |
gptkb:National_Cancer_Institute
|
| gptkbp:has_stereochemistry |
Z-isomer
|
| gptkbp:hasSMILES |
CC/C(=C(/C1=CC=CC=C1)C2=CC=C(C=C2)O)/C3=CC=CC=N3
|
| https://www.w3.org/2000/01/rdf-schema#label |
Z-endoxifen
|
| gptkbp:mechanismOfAction |
estrogen receptor antagonist
|
| gptkbp:metabolism |
gptkb:tamoxifen
|
| gptkbp:molecularWeight |
373.49 g/mol
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL2103837
11556311 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:synonym |
gptkb:endoxifen
(Z)-4-hydroxy-N-desmethyltamoxifen |
| gptkbp:target |
estrogen receptor alpha
estrogen receptor beta |
| gptkbp:UNII |
6QX8J75Z1U
|
| gptkbp:usedFor |
gptkb:cancer
|
| gptkbp:bfsParent |
gptkb:endoxifen
|
| gptkbp:bfsLayer |
7
|