|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
PRP43
|
|
gptkbp:conservedIn
|
gptkb:DEAD-box_helicase_domain
Helicase C-terminal domain
|
|
gptkbp:describes
|
DEAD-box RNA helicase involved in pre-mRNA splicing and ribosome biogenesis
|
|
gptkbp:encodes
|
PRP43
|
|
gptkbp:essentialGene
|
yes
|
|
gptkbp:expressedIn
|
constitutive
|
|
gptkbp:firstPublished
|
1990
|
|
gptkbp:foundIn
|
gptkb:Saccharomyces_cerevisiae
|
|
gptkbp:function
|
ribosome biogenesis
pre-mRNA splicing
RNA helicase activity
|
|
gptkbp:geneType
|
protein_coding
|
|
gptkbp:GO:0000398
|
mRNA splicing, via spliceosome
|
|
gptkbp:GO:0003676
|
nucleic acid binding
|
|
gptkbp:GO:0004386
|
helicase activity
|
|
gptkbp:GO:0005681
|
spliceosomal complex
|
|
gptkbp:GO:0006364
|
rRNA processing
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
YGL120C
|
|
gptkbp:interactsWith
|
gptkb:U2_snRNP
U5 snRNP
U6 snRNP
Nop1
Nop56
Nop58
Snu114
|
|
gptkbp:length
|
767 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:Chromosome_VII
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
87.6 kDa
|
|
gptkbp:mutationAssociatedWith
|
slow growth
temperature sensitive
defective pre-mRNA splicing
defective ribosome biogenesis
|
|
gptkbp:organism
|
Saccharomyces cerevisiae S288C
|
|
gptkbp:orthologIn
|
human DHX15
|
|
gptkbp:pathway
|
ribosome biogenesis pathway
spliceosome pathway
|
|
gptkbp:regulates
|
regulated by transcription factors
regulated by nutrient availability
regulated by cell cycle
|
|
gptkbp:sequenceStatus
|
verified
|
|
gptkbp:SGDID
|
S000003054
|
|
gptkbp:standardizedBy
|
PRP43
|
|
gptkbp:strand
|
gptkb:Crick
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
nucleolus
|
|
gptkbp:systematicName
|
gptkb:YGL120C
|
|
gptkbp:bfsParent
|
gptkb:Chromosome_VII
|
|
gptkbp:bfsLayer
|
8
|