Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:clinical_trial
research |
| gptkbp:age |
postmenopausal women aged 50-79
|
| gptkbp:country |
gptkb:United_States
|
| gptkbp:eligibility |
1993-1998
|
| gptkbp:endDate |
ongoing (follow-up studies)
|
| gptkbp:focus |
gptkb:cancer
gptkb:cardiovascular_disease gptkb:bone hormone therapy calcium and vitamin D supplementation dietary modification postmenopausal women’s health |
| https://www.w3.org/2000/01/rdf-schema#label |
Women’s Health Initiative
|
| gptkbp:impact |
influenced public health policy
changed clinical guidelines for hormone therapy |
| gptkbp:location |
gptkb:United_States
|
| gptkbp:notableFinds |
dietary fat reduction did not significantly reduce risk of heart disease
hormone therapy increases risk of blood clots hormone therapy increases risk of breast cancer hormone therapy increases risk of stroke calcium and vitamin D supplementation did not significantly reduce risk of fractures hormone therapy does not reduce risk of heart disease |
| gptkbp:participants |
over 160,000
|
| gptkbp:principalInvestigator |
gptkb:Dr._Jacques_Rossouw
gptkb:Dr._Garnet_Anderson |
| gptkbp:sponsor |
gptkb:National_Institutes_of_Health
|
| gptkbp:startDate |
1991
|
| gptkbp:studyType |
gptkb:clinical_trial
observational study |
| gptkbp:website |
https://www.whi.org/
|
| gptkbp:bfsParent |
gptkb:NHLBI
|
| gptkbp:bfsLayer |
6
|