Women's Health Initiative

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:clinical_trial
research
gptkbp:affiliation National Heart, Lung, and Blood Institute
gptkbp:country gptkb:United_States
gptkbp:eligibility 1993-1998
gptkbp:focus gptkb:cancer
gptkb:cardiovascular_disease
gptkb:bone
chronic disease prevention
hormone therapy
calcium and vitamin D supplementation
dietary modification
postmenopausal women
https://www.w3.org/2000/01/rdf-schema#label Women's Health Initiative
gptkbp:impact influenced public health policy
changed clinical guidelines for hormone therapy
gptkbp:location gptkb:United_States
gptkbp:notableFinds calcium and vitamin D supplementation had limited effect on fracture risk
hormone therapy increased risk of breast cancer
hormone therapy increased risk of heart disease
hormone therapy increased risk of stroke
dietary fat reduction did not significantly reduce risk of heart disease
gptkbp:participants over 160,000
gptkbp:principalInvestigator gptkb:Dr._Jacques_Rossouw
gptkbp:publishedIn gptkb:New_England_Journal_of_Medicine
gptkb:JAMA
gptkbp:sponsor gptkb:National_Institutes_of_Health
gptkbp:startDate 1991
gptkbp:studyType gptkb:clinical_trial
observational study
gptkbp:website https://www.whi.org/
gptkbp:bfsParent gptkb:Bernadine_Healy
gptkbp:bfsLayer 5