Whipple disease

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects central nervous system
digestive system
joints
immune system
gptkbp:alsoKnownAs intestinal lipodystrophy
gptkbp:category bacterial infectious disease
gptkbp:causedBy Tropheryma whipplei
gptkbp:complication relapse
neurological involvement
gptkbp:diagnosedBy PAS-positive macrophages
PCR for Tropheryma whipplei
small intestine biopsy
gptkbp:firstDescribed gptkb:George_Hoyt_Whipple
1907
gptkbp:hasEpidemiology more common in middle-aged men
https://www.w3.org/2000/01/rdf-schema#label Whipple disease
gptkbp:ICD-10_code K90.81
gptkbp:mortalityWithoutTreatment high
gptkbp:mortalityWithTreatment low
gptkbp:rareDisease true
gptkbp:symptom fever
diarrhea
abdominal pain
weight loss
arthralgia
malabsorption
gptkbp:transmission unknown
gptkbp:treatment gptkb:ceftriaxone
gptkb:trimethoprim-sulfamethoxazole
antibiotics
gptkbp:bfsParent gptkb:Whipple
gptkbp:bfsLayer 7