Properties (49)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:Company
|
gptkbp:activeDuring |
rofecoxib
|
gptkbp:approves |
pain relief
rheumatoid arthritis osteoarthritis acute_pain |
gptkbp:associatedWith |
cardiovascular risks
|
gptkbp:class |
COX-2 inhibitor
|
gptkbp:clinicalTrials |
yes
short-term treatment menstrual pain post-operative pain long-term treatment migraine relief treatment of gout |
gptkbp:deployedTo |
increased risk of heart attack
increased risk of stroke |
gptkbp:developedBy |
gptkb:Merck_&_Co.
|
gptkbp:discontinued |
2004
|
gptkbp:dosageForm |
50 mg
25 mg 12.5 mg |
gptkbp:exportMarkets |
2004
|
gptkbp:formulation |
oral tablet
|
https://www.w3.org/2000/01/rdf-schema#label |
Vioxx
|
gptkbp:internationalClassification |
allergic reactions
liver damage skin reactions kidney problems adverse reactions |
gptkbp:lastProduced |
1999
|
gptkbp:legalStatus |
lawsuits
settlements |
gptkbp:marketedAs |
gptkb:Canada
gptkb:European_Union gptkb:United_States anti-inflammatory medication pain reliever Vioxx_brand_name |
gptkbp:patentExpiration |
2009
|
gptkbp:recalls |
safety concerns
|
gptkbp:replacedBy |
other NSAIDs
|
gptkbp:researchInterest |
ongoing
|
gptkbp:sideEffect |
heart attack
stroke gastrointestinal issues |
gptkbp:targets |
inflammation
pain |
gptkbp:usedFor |
chronic pain management
|