Velo-Cardio-Facial Syndrome

GPTKB entity

Statements (47)
Predicate Object
gptkbp:instanceOf gptkb:syndrome
gptkb:genetic_disorder
gptkbp:affects adults
children
gptkbp:alsoKnownAs gptkb:DiGeorge_syndrome
gptkb:22q11.2_deletion_syndrome
gptkbp:associatedWith gptkb:congenital_heart_disease
short stature
hearing loss
seizures
developmental delay
feeding difficulties
learning difficulties
immune deficiency
hypocalcemia
growth hormone deficiency
kidney abnormalities
hypernasal speech
dysmorphic facial features
palatal abnormalities
psychiatric illness
gptkbp:causedBy deletion on chromosome 22q11.2
gptkbp:diagnosedBy genetic testing
gptkbp:firstDescribed gptkb:Angelo_DiGeorge
1968
gptkbp:ICD-10_code D82.1
gptkbp:inheritance autosomal dominant
gptkbp:OMIM 192430
gptkbp:prevalence 1 in 4000 live births
gptkbp:riskFactor gptkb:autism_spectrum_disorder
schizophrenia
anxiety disorders
psychiatric disorders
gptkbp:symptom distinct facial features
learning disabilities
heart defects
developmental delay
cleft palate
speech difficulties
immune system problems
gptkbp:treatment special education
speech therapy
surgical intervention
symptomatic management
gptkbp:bfsParent gptkb:Life_with_VCFS_documentary
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label Velo-Cardio-Facial Syndrome

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