VLDL-R

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeSplicing yes
gptkbp:associatedWith cerebellar hypoplasia and mental retardation
gptkbp:binds apolipoprotein E-containing lipoproteins
gptkbp:discoveredBy 1992
gptkbp:doesNotBind gptkb:LDL
gptkbp:encodedBy gptkb:VLDLR_gene
gptkbp:expressedIn gptkb:skeletal_muscle
brain
heart
adipose tissue
gptkbp:foundIn humans
mammals
gptkbp:fullName Very Low-Density Lipoprotein Receptor
gptkbp:function mediates endocytosis of VLDL
receptor for very low-density lipoproteins
gptkbp:gene gptkb:VLDLR
https://www.w3.org/2000/01/rdf-schema#label VLDL-R
gptkbp:locatedOnChromosome chromosome 9p24
gptkbp:location gptkb:cell_membrane
gptkbp:memberOf gptkb:LDL_receptor_family
gptkbp:OMIM 192977
gptkbp:orthologIn gptkb:LDL_receptor
gptkbp:relatedTo gptkb:Reelin_signaling_pathway
atherosclerosis
lipid metabolism
gptkbp:structure contains EGF-like domains
contains O-linked sugar domain
contains ligand-binding repeats
gptkbp:UniProtID P98155
gptkbp:bfsParent gptkb:VLDLR
gptkbp:bfsLayer 7