Statements (47)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
4
|
| gptkbp:bfsParent |
gptkb:methotrexate
|
| gptkbp:activities |
inhibits dihydrofolate reductase
|
| gptkbp:approves |
1953
|
| gptkbp:brand |
gptkb:Rheumatrex
gptkb:Otrexup Xatmep |
| gptkbp:category |
gptkb:X
|
| gptkbp:class |
gptkb:fragrance
gptkb:drug |
| gptkbp:contraindication |
alcohol consumption
pregnancy |
| gptkbp:dosage_form |
10 mg
oral tablet 50 mg 15 mg 25 mg 2.5 mg |
| gptkbp:education |
avoid alcohol
stay hydrated report signs of infection regular blood tests required |
| gptkbp:formulation |
gptkb:tablet
|
| https://www.w3.org/2000/01/rdf-schema#label |
Trexall
|
| gptkbp:ingredients |
gptkb:methotrexate
|
| gptkbp:interacts_with |
antibiotics
live vaccines NSAI Ds sulfonamides |
| gptkbp:is_monitored_by |
liver function tests
complete blood count renal function tests |
| gptkbp:is_used_for |
treatment of psoriasis
treatment of rheumatoid arthritis |
| gptkbp:lifespan |
8 to 15 hours
|
| gptkbp:manager |
oral
|
| gptkbp:manufacturer |
various pharmaceutical companies
|
| gptkbp:metabolism |
hepatic
|
| gptkbp:requires |
prescription only
|
| gptkbp:rounds |
renal
|
| gptkbp:side_effect |
fatigue
nausea liver toxicity mouth sores |
| gptkbp:social_structure |
C20 H22 N8 O5
|
| gptkbp:storage |
room temperature
|