Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:plasma_protein
gptkb:protein |
| gptkbp:abbreviation |
gptkb:TBG
|
| gptkbp:alternativeName |
Thyroid hormone-binding globulin
|
| gptkbp:associatedWith |
TBG deficiency
TBG excess |
| gptkbp:binds |
gptkb:triiodothyronine_(T3)
thyroxine (T4) |
| gptkbp:discoveredBy |
Rosemary Pitt-Rivers
|
| gptkbp:discoveredIn |
1959
|
| gptkbp:encodedBy |
gptkb:SERPINA7_gene
|
| gptkbp:family |
serpin family
|
| gptkbp:foundIn |
blood plasma
|
| gptkbp:function |
transports thyroid hormones in blood
|
| gptkbp:halfLife |
5 days
|
| gptkbp:highestAffinity |
thyroxine (T4)
|
| gptkbp:locatedOnChromosome |
Xq22.3
|
| gptkbp:molecularWeight |
54 kDa
|
| gptkbp:OMIM |
314200
|
| gptkbp:percentageOfThyroidHormoneBound |
~70% of T3 in plasma
~75% of T4 in plasma |
| gptkbp:significance |
altered levels affect thyroid function tests
|
| gptkbp:structure |
single polypeptide chain
|
| gptkbp:synthesisType |
liver
|
| gptkbp:UniProtID |
P05543
|
| gptkbp:bfsParent |
gptkb:TBG
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Thyroxine-binding globulin
|