Thromboxane A2

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf eicosanoid
thromboxane
gptkbp:actsOn thromboxane receptor
gptkbp:biosynthesized_from prostaglandin H2
gptkbp:category lipid mediator
gptkbp:chemicalFormula C20H32O5
gptkbp:degradedBy thromboxane B2
gptkbp:discoveredBy 1975
gptkbp:enzyme_for_synthesis thromboxane-A synthase
gptkbp:foundIn mammals
gptkbp:function vasoconstriction
promotes platelet aggregation
gptkbp:halfLife ~30 seconds
https://www.w3.org/2000/01/rdf-schema#label Thromboxane A2
gptkbp:inhibitedBy gptkb:aspirin
gptkbp:IUPACName (5Z,13E,15S)-6,9-epoxy-11α,15-dihydroxyprosta-5,13-dienoic acid
gptkbp:MeSH_ID D013927
gptkbp:predecessor gptkb:arachidonic_acid
gptkbp:producedBy platelets
gptkbp:PubChem_CID 5280497
CHEBI:15627
gptkbp:relatedTo prostaglandins
prostacyclin
gptkbp:role thrombosis
hemostasis
gptkbp:UNII 1S9WJ6QF6F
gptkbp:bfsParent gptkb:Platelet
gptkbp:bfsLayer 5