|
gptkbp:instanceOf
|
gptkb:Dragon
gptkb:chemical_compound
|
|
gptkbp:antidote
|
no known antidote
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:CASNumber
|
4368-28-9
|
|
gptkbp:category
|
gptkb:heterocyclic_compound
gptkb:alkaloid
marine toxin
guanidine derivative
|
|
gptkbp:chemicalFormula
|
C11H17N3O8
|
|
gptkbp:discoveredBy
|
gptkb:Yoshizumi_Tahara
|
|
gptkbp:discoveredIn
|
1909
|
|
gptkbp:effectOnHumans
|
can cause death
causes paralysis
|
|
gptkbp:flavor
|
tasteless
|
|
gptkbp:foundIn
|
gptkb:fish
gptkb:rough-skinned_newt
gptkb:blue-ringed_octopus
horseshoe crabs
moon snails
|
|
gptkbp:IUPACName
|
(3α,4β,6α,8α,9α)-octahydro-6,8,9-trihydroxy-3-(hydroxymethyl)imidazo[1,2-a]pyrrolo[2,1-c][1,4]oxazin-5(1H)-one
|
|
gptkbp:LD50
|
10 μg/kg (mouse, intravenous)
|
|
gptkbp:mechanismOfAction
|
blocks voltage-gated sodium channels
|
|
gptkbp:molecularWeight
|
319.27 g/mol
|
|
gptkbp:notableEvent
|
fugu poisoning in Japan
|
|
gptkbp:producedBy
|
symbiotic bacteria in host animals
|
|
gptkbp:PubChem_CID
|
5793
|
|
gptkbp:relatedTo
|
batrachotoxin
saxitoxin
|
|
gptkbp:riskFactor
|
highly hazardous
|
|
gptkbp:routeOfExposure
|
injection
oral
inhalation
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:stable
|
heat-stable
acid-stable
|
|
gptkbp:symptomsOfPoisoning
|
gptkb:arrhythmia
respiratory failure
dizziness
numbness
|
|
gptkbp:toxicity
|
highly toxic
|
|
gptkbp:treatment
|
supportive care
mechanical ventilation
|
|
gptkbp:uses
|
neuroscience research
pharmacological tool
|
|
gptkbp:bfsParent
|
gptkb:Blue-ringed_octopus
gptkb:TTX
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tetrodotoxin
|