Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
gptkb:chemical_compound |
| gptkbp:antidote |
no known antidote
|
| gptkbp:aroma |
odorless
|
| gptkbp:CASNumber |
4368-28-9
|
| gptkbp:category |
alkaloid
heterocyclic compound marine toxin guanidine derivative |
| gptkbp:chemicalFormula |
C11H17N3O8
|
| gptkbp:discoveredBy |
gptkb:Yoshizumi_Tahara
|
| gptkbp:discoveredIn |
1909
|
| gptkbp:effectOnHumans |
can cause death
causes paralysis |
| gptkbp:flavor |
tasteless
|
| gptkbp:foundIn |
gptkb:fish
gptkb:rough-skinned_newt gptkb:blue-ringed_octopus horseshoe crabs moon snails |
| https://www.w3.org/2000/01/rdf-schema#label |
Tetrodotoxin
|
| gptkbp:IUPACName |
(3α,4β,6α,8α,9α)-octahydro-6,8,9-trihydroxy-3-(hydroxymethyl)imidazo[1,2-a]pyrrolo[2,1-c][1,4]oxazin-5(1H)-one
|
| gptkbp:LD50 |
10 μg/kg (mouse, intravenous)
|
| gptkbp:mechanismOfAction |
blocks voltage-gated sodium channels
|
| gptkbp:molecularWeight |
319.27 g/mol
|
| gptkbp:notableEvent |
fugu poisoning in Japan
|
| gptkbp:producedBy |
symbiotic bacteria in host animals
|
| gptkbp:PubChem_CID |
5793
|
| gptkbp:relatedTo |
batrachotoxin
saxitoxin |
| gptkbp:riskFactor |
highly hazardous
|
| gptkbp:routeOfExposure |
injection
oral inhalation |
| gptkbp:solubility |
water soluble
|
| gptkbp:stable |
heat-stable
acid-stable |
| gptkbp:symptomsOfPoisoning |
gptkb:arrhythmia
respiratory failure dizziness numbness |
| gptkbp:toxicity |
highly toxic
|
| gptkbp:treatment |
supportive care
mechanical ventilation |
| gptkbp:uses |
neuroscience research
pharmacological tool |
| gptkbp:bfsParent |
gptkb:Blue-ringed_octopus
|
| gptkbp:bfsLayer |
5
|