|
gptkbp:instance_of
|
gptkb:blockade
|
|
gptkbp:approves
|
gptkb:1978
|
|
gptkbp:atccode
|
C07 AB12
|
|
gptkbp:bioavailability
|
50% to 60%
|
|
gptkbp:brand
|
gptkb:Tenormin
|
|
gptkbp:casnumber
|
29122-68-7
|
|
gptkbp:category
|
gptkb:D
|
|
gptkbp:chemical_formula
|
C14 H22 N2 O3 S
|
|
gptkbp:class
|
selective beta-1 adrenergic antagonist
|
|
gptkbp:clinical_trial
|
Phase IV
|
|
gptkbp:contraindication
|
gptkb:asthma
heart block
severe bradycardia
|
|
gptkbp:dosage_form
|
gptkb:tablet
25 mg to 100 mg daily
|
|
gptkbp:drug_interactions
|
gptkb:diabetes
calcium channel blockers
other antihypertensives
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tenormin
|
|
gptkbp:ingredients
|
gptkb:atenolol
|
|
gptkbp:legal_status
|
prescription only
|
|
gptkbp:lifespan
|
6 to 7 hours
|
|
gptkbp:manufacturer
|
gptkb:Astra_Zeneca
|
|
gptkbp:mechanism_of_action
|
blocks beta-1 adrenergic receptors
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:route_of_administration
|
oral
|
|
gptkbp:side_effect
|
gptkb:depression
dizziness
fatigue
bradycardia
cold extremities
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:used_for
|
hypertension
angina pectoris
heart attack prevention
|
|
gptkbp:bfsParent
|
gptkb:atenolol
|
|
gptkbp:bfsLayer
|
7
|