Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Matrix
|
| gptkbp:associated_with |
cardiovascular diseases
cancer progression |
| gptkbp:breeding_behavior |
other species
|
| gptkbp:clinical_trial |
biomarker for diseases
|
| gptkbp:discovered_by |
human studies
|
| gptkbp:form |
TIMP-4 A
|
| gptkbp:function |
inhibits matrix metalloproteinases
|
| https://www.w3.org/2000/01/rdf-schema#label |
TIMP-4
|
| gptkbp:influences |
cell migration
|
| gptkbp:inhibitory_effect |
angiogenesis
|
| gptkbp:interacts_with |
metalloproteinases
|
| gptkbp:involved_in |
wound healing
inflammatory responses |
| gptkbp:is_expressed_in |
gptkb:Brain
gptkb:Heart kidney liver lung regulated by growth factors |
| gptkbp:is_involved_in |
gptkb:neurodegenerative_diseases
apoptosis cell differentiation cell proliferation cell signaling cellular stress response immune response metabolic disorders chronic diseases tumorigenesis cell survival tumor microenvironment cellular aging organ development chronic inflammation vascular remodeling tissue repair cell adhesion metastasis therapeutic targets pathological conditions tissue homeostasis cellular interactions angiogenic switch tumor invasion neoplastic processes extracellular matrix turnover metalloproteinase regulation |
| gptkbp:is_linked_to |
fibrosis
|
| gptkbp:is_part_of |
extracellular matrix regulation
|
| gptkbp:is_regulated_by |
hormones
|
| gptkbp:location |
extracellular space
|
| gptkbp:produced_by |
various tissues
|
| gptkbp:promoter |
TIMP4
|
| gptkbp:related_to |
TIMP family
|
| gptkbp:role |
tissue remodeling
|
| gptkbp:bfsParent |
gptkb:MMP2
|
| gptkbp:bfsLayer |
8
|