Statements (19)
Predicate | Object |
---|---|
gptkbp:instanceOf |
immunotherapy
|
gptkbp:alsoKnownAs |
SAR444245
|
gptkbp:amendedBy |
PEGylated IL-2 variant
|
gptkbp:clinicalTrialPhase |
Phase 1
NCT04009681 |
gptkbp:designedFor |
reduce toxicity compared to native IL-2
stimulate immune response against tumors |
gptkbp:developedBy |
gptkb:Sanofi
gptkb:Synthorx |
https://www.w3.org/2000/01/rdf-schema#label |
THOR-707
|
gptkbp:indication |
gptkb:cancer
|
gptkbp:mechanismOfAction |
IL-2 pathway agonist
selective IL-2Rβγ agonist |
gptkbp:origin |
engineered protein
|
gptkbp:routeOfAdministration |
intravenous
|
gptkbp:status |
investigational drug
|
gptkbp:target |
interleukin-2 receptor beta-gamma
|
gptkbp:bfsParent |
gptkb:Synthorx
|
gptkbp:bfsLayer |
8
|