TBP-associated factors (TAFs)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:TAFs TBP-associated factors
gptkbp:binds	gptkb:TATA-binding_protein_(TBP)
gptkbp:component	gptkb:TFIID
gptkbp:discoveredIn	1990s
gptkbp:encodedBy	TAF genes
gptkbp:example	gptkb:TAF1 gptkb:TAF10 gptkb:TAF11 gptkb:TAF12 gptkb:TAF13 gptkb:TAF2 gptkb:TAF4 gptkb:TAF5 gptkb:TAF6 gptkb:TAF7 gptkb:TAF8 gptkb:TAF9 gptkb:TAF15
gptkbp:foundIn	eukaryotes
gptkbp:function	transcription regulation
https://www.w3.org/2000/01/rdf-schema#label	TBP-associated factors (TAFs)
gptkbp:interactsWith	transcription factors chromatin coactivators
gptkbp:involvedIn	RNA polymerase II transcription initiation
gptkbp:locale	gptkb:nucleus
gptkbp:modulatedBy	transcriptional activation promoter recognition transcriptional repression
gptkbp:numberOfSubunits	13 (in humans)
gptkbp:participatedIn	chromatin remodeling histone acetylation core promoter binding
gptkbp:regulates	gene expression
gptkbp:requires	preinitiation complex assembly
gptkbp:structure	multi-protein complex
gptkbp:subunit	gptkb:TFIID_complex
gptkbp:bfsParent	gptkb:GTF2D gptkb:transcription_factor_IID_(TFIID)
gptkbp:bfsLayer	7