TAILORx Trial

GPTKB entity

Statements (109)
Predicate Object
gptkbp:instance_of gptkb:Clinical_Trials
gptkbp:aims_to_determine the benefit of chemotherapy
gptkbp:aims_to_improve unnecessary chemotherapy
gptkbp:analyzes recurrence scores
gptkbp:collaborated_with academic institutions
pharmaceutical companies
international researchers
international research groups
gptkbp:completed gptkb:2015
gptkbp:concluded_on many women can skip chemotherapy
gptkbp:conducted multiple countries
multidisciplinary teams
clinical settings
gptkbp:contributes_to breast cancer treatment protocols
gptkbp:evaluates the necessity of chemotherapy
the role of genomic testing
gptkbp:examines gptkb:hormone_receptor-positive_breast_cancer
gptkbp:excludes HER2-positive patients
gptkbp:findings_impact treatment guidelines
gptkbp:focuses_on gptkb:Oncology
gptkbp:has_ethical_approval_from institutional review boards
gptkbp:has_follow_up_studies ongoing research projects
gptkbp:has_impact_on personalized medicine
breast cancer treatment guidelines
gptkbp:has_implications_for personalized treatment plans
gptkbp:has_led_to new treatment strategies
gptkbp:has_long_term_follow_up to assess outcomes
gptkbp:has_sample_size_of over 10,000 women
https://www.w3.org/2000/01/rdf-schema#label TAILORx Trial
gptkbp:includes postmenopausal women
gptkbp:influences patient decision-making
gptkbp:involves over 10,000 women
women with early-stage breast cancer
gptkbp:involves_patients_with gptkb:hormone_receptor-positive_breast_cancer
gptkbp:is_a_guide_for clinical decisions
gptkbp:is_analyzed_in statistical methods
cost-effectiveness
systematic reviews
adverse effects
long-term effects
gptkbp:is_associated_with improved patient outcomes
quality of life assessments
improved treatment outcomes.
reduced chemotherapy use
gptkbp:is_cited_in numerous research articles
numerous medical publications
gptkbp:is_collaborative_with various cancer research institutions
various cancer centers
gptkbp:is_considered landmark study
gptkbp:is_discussed_in gptkb:literature
gptkb:healthcare_professionals
patient forums
gptkbp:is_documented_in gptkb:guidelines
clinical trial databases
clinical trial reports
gptkbp:is_evaluated_by peer review process
treatment efficacy
cost-effectiveness
peer-reviewed studies
quality of life outcomes
gptkbp:is_funded_by gptkb:American_Society_of_Clinical_Oncology
NCI and other organizations
gptkbp:is_influenced_by advancements in genomics
gptkbp:is_influential_in oncology practices
clinical practice changes
shaping treatment protocols
gptkbp:is_informed_by patient feedback
gptkbp:is_led_by gptkb:Dr._Joseph_A._Sparano
gptkbp:is_linked_to survival rates
gptkbp:is_monitored_by gptkb:data_safety_monitoring_board
gptkbp:is_part_of cancer treatment research
cancer research funding initiatives
breast cancer research initiatives
larger research initiative
evidence-based medicine practices
breast cancer research agenda
precision medicine approach
NCT number NCT00310180
gptkbp:is_recognized_by medical community
gptkbp:is_recognized_for its innovative approach
its contribution to oncology
gptkbp:is_related_to precision medicine
breast cancer survival rates
gptkbp:is_reviewed_by regulatory bodies
medical experts
gptkbp:is_supported_by non-profit organizations
pharmaceutical companies
government funding
patient advocacy groups
research grants
gptkbp:is_utilized_by oncologists
gptkbp:is_utilized_for patient stratification
gptkbp:is_utilized_in treatment planning
treatment decision-making
gptkbp:participants multiple countries
gptkbp:presented_by medical conferences
gptkbp:provides_information_on future research
future breast cancer studies
gptkbp:published_by gptkb:The_New_England_Journal_of_Medicine
clinical trial registries
gptkbp:published_in gptkb:New_England_Journal_of_Medicine
gptkbp:reported_by gptkb:media_outlets
clinical trial registries
medical conferences
clinical trial databases
gptkbp:result gptkb:2018
gptkbp:sponsored_by gptkb:National_Institutes_of_Health
gptkbp:started_in gptkb:2006
gptkbp:uses Oncotype DX test