Statements (13)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
mutant
|
| gptkbp:aminoAcidChange |
threonine to methionine at position 790
|
| gptkbp:associatedWith |
gptkb:non-small_cell_lung_cancer
|
| gptkbp:detects |
molecular testing
|
| gptkbp:firstDescribed |
2005
|
| gptkbp:foundIn |
gptkb:EGFR_gene
|
| gptkbp:frequencyInAcquiredResistance |
~50%
|
| https://www.w3.org/2000/01/rdf-schema#label |
T790M
|
| gptkbp:notableFor |
exon 20 of EGFR
|
| gptkbp:resistantTo |
gptkb:EGFR_tyrosine_kinase_inhibitors
|
| gptkbp:target |
gptkb:osimertinib
|
| gptkbp:bfsParent |
gptkb:EGFR_mutation
|
| gptkbp:bfsLayer |
5
|