|
gptkbp:instanceOf
|
gptkb:antibiotic
sulfonamide
|
|
gptkbp:ATCCode
|
J01EC02
|
|
gptkbp:CASNumber
|
68-35-9
|
|
gptkbp:chemicalFormula
|
C10H10N4O2S
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
pregnancy
severe kidney disease
severe liver disease
sulfa allergy
|
|
gptkbp:discoveredBy
|
gptkb:Daniel_Bovet
|
|
gptkbp:discoveredIn
|
1938
|
|
gptkbp:eliminationHalfLife
|
7-17 hours
|
|
gptkbp:excretion
|
renal
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sulfadiazine
|
|
gptkbp:IUPACName
|
4-amino-N-pyrimidin-2-yl-benzenesulfonamide
|
|
gptkbp:KEGGID
|
D00454
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits dihydropteroate synthase
|
|
gptkbp:meltingPoint
|
254°C
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
250.28 g/mol
|
|
gptkbp:pregnancyCategory
|
D
|
|
gptkbp:PubChem_CID
|
5333
CHEMBL1387
DB00359
|
|
gptkbp:routeOfAdministration
|
oral
topical
|
|
gptkbp:sideEffect
|
nausea
vomiting
allergic reaction
crystalluria
|
|
gptkbp:solubility
|
poor
|
|
gptkbp:synonym
|
Sulfadiazina
Sulfadiazineum
Sulfadiazinum
|
|
gptkbp:UNII
|
6Q87F2C34Y
|
|
gptkbp:usedFor
|
gptkb:toxoplasmosis
urinary tract infections
nocardiosis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Toxoplasmosis
|
|
gptkbp:bfsLayer
|
5
|