|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:complex_II
gptkb:succinate-coenzyme_Q_reductase
|
|
gptkbp:associatedWith
|
gptkb:Leigh_syndrome
gptkb:pheochromocytoma
gptkb:mitochondrial_complex_II_deficiency
paraganglioma
|
|
gptkbp:biologicalProcess
|
oxidoreductase activity
|
|
gptkbp:catalyzes
|
oxidation of succinate to fumarate
|
|
gptkbp:cofactor
|
gptkb:FAD
iron-sulfur clusters
|
|
gptkbp:component
|
electron transport chain
citric acid cycle
|
|
gptkbp:discoveredBy
|
gptkb:Albert_Szent-Györgyi
|
|
gptkbp:discoveredIn
|
1937
|
|
gptkbp:EC_number
|
1.3.5.1
|
|
gptkbp:electronAcceptor
|
ubiquinone
|
|
gptkbp:eukaryotePresence
|
yes
|
|
gptkbp:gene
|
gptkb:SDHA
gptkb:SDHB
gptkb:SDHC
gptkb:SDHD
|
|
gptkbp:GO_term
|
GO:0008177
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Succinate dehydrogenase
|
|
gptkbp:inhibitedBy
|
gptkb:oxaloacetate
malonate
|
|
gptkbp:location
|
inner mitochondrial membrane
|
|
gptkbp:product
|
fumarate
|
|
gptkbp:prokaryotePresence
|
yes
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:substrate
|
succinate
|
|
gptkbp:subunit
|
gptkb:SDHA
gptkb:SDHB
gptkb:SDHC
gptkb:SDHD
|
|
gptkbp:bfsParent
|
gptkb:Enzymes
|
|
gptkbp:bfsLayer
|
6
|