Squamous Cell Carcinoma of the Esophagus

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:cancer
Esophageal cancer
gptkbp:associatedWith Chronic esophagitis
Human papillomavirus (HPV) infection
Tylosis
gptkbp:canMetastasizeTo gptkb:bone
Liver
Lung
Lymph nodes
gptkbp:diagnosedBy gptkb:Barium_swallow
gptkb:CT_scan
Biopsy
Endoscopy
gptkbp:differentialDiagnosis gptkb:Esophagitis
Adenocarcinoma of the esophagus
Benign esophageal stricture
gptkbp:diseaseLocation Esophagus
gptkbp:firstDescribed 19th century
gptkbp:hasEpidemiology More common in males
Incidence increases with age
More common in Asia and Africa
gptkbp:hasScreening Not routinely recommended
gptkbp:histology Malignant squamous cells
https://www.w3.org/2000/01/rdf-schema#label Squamous Cell Carcinoma of the Esophagus
gptkbp:ICD-10_code C15.1
gptkbp:location Upper and middle third of esophagus
gptkbp:predecessor Dysplasia of esophageal squamous epithelium
gptkbp:prognosis Generally poor
5-year survival rate is low
gptkbp:riskFactor gptkb:Plummer-Vinson_syndrome
Alcohol consumption
Tobacco smoking
Achalasia
Consumption of very hot liquids
Diet low in fruits and vegetables
Nitrosamine exposure
gptkbp:stageName gptkb:TNM_staging
gptkbp:symptom gptkb:Odynophagia
Weight loss
Cough
Hoarseness
Dysphagia
Chest pain
gptkbp:treatment radiation therapy
Surgery
Chemotherapy
Palliative care
gptkbp:bfsParent gptkb:cancer
gptkbp:bfsLayer 4