Statements (61)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
birth defect
neural tube defect |
| gptkbp:affects |
gptkb:spinal_cord
infants vertebral column |
| gptkbp:cause |
gptkb:depression
gptkb:Arnold-Chiari_malformation hydrocephalus paralysis cognitive impairment scoliosis social challenges skin problems sexual dysfunction learning difficulties urinary tract infections clubfoot pressure sores orthopedic problems mobility impairment bladder problems bowel problems latex allergy tethered spinal cord |
| gptkbp:causedBy |
incomplete closure of neural tube
|
| gptkbp:diagnosedBy |
amniocentesis
prenatal ultrasound alpha-fetoprotein test |
| gptkbp:firstDescribed |
17th century
|
| gptkbp:frequency |
about 1 in 1,000 births
|
| gptkbp:hasType |
meningocele
myelomeningocele spina bifida occulta |
| https://www.w3.org/2000/01/rdf-schema#label |
Spina bifida
|
| gptkbp:ICD-10_code |
Q05
|
| gptkbp:MeSH_ID |
D013116
|
| gptkbp:OMIM |
182940
|
| gptkbp:prevention |
folic acid supplementation
|
| gptkbp:riskFactor |
family history
certain medications obesity maternal diabetes folic acid deficiency |
| gptkbp:symptom |
hydrocephalus
seizures learning difficulties urinary incontinence loss of sensation curvature of the spine abnormal gait bowel incontinence fluid-filled sac on back open lesion on back orthopedic deformities weakness in legs |
| gptkbp:treatment |
surgery
physical therapy assistive devices catheterization |
| gptkbp:bfsParent |
gptkb:Club_Foot
|
| gptkbp:bfsLayer |
6
|