Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:component |
gptkb:plasma_membrane
|
| gptkbp:discoveredBy |
Mary Beckerle
|
| gptkbp:discoveredIn |
1971
|
| gptkbp:domain |
spectrin repeat
|
| gptkbp:form |
heterodimer
tetramer |
| gptkbp:foundIn |
cytoskeleton
erythrocytes |
| gptkbp:function |
maintains cell shape
provides mechanical support |
| gptkbp:gene |
gptkb:SPTA1
gptkb:SPTB SPTAN1 SPTBN1 |
| https://www.w3.org/2000/01/rdf-schema#label |
Spectrin
|
| gptkbp:interactsWith |
gptkb:actin
gptkb:ankyrin |
| gptkbp:length |
200-260 nm
|
| gptkbp:mutationAssociatedWith |
gptkb:hereditary_elliptocytosis
gptkb:hereditary_spherocytosis |
| gptkbp:presentIn |
neurons
muscle cells epithelial cells |
| gptkbp:role |
vesicle trafficking
cell signaling cell adhesion membrane stability |
| gptkbp:structure |
flexible rod
|
| gptkbp:subunit |
alpha spectrin
beta spectrin |
| gptkbp:bfsParent |
gptkb:Red_Blood_Cell
|
| gptkbp:bfsLayer |
6
|