Properties (56)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Protein
|
| gptkbp:associated_with |
Hormonal regulation
Caloric restriction Hormonal balance Oxidative stress response Metabolic flexibility |
| gptkbp:function |
Regulate cellular processes
|
| gptkbp:has_a_role_in |
Cell survival
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sirtuins
|
| gptkbp:includes |
gptkb:SIRT1
SIRT2 SIRT3 SIRT4 SIRT5 SIRT6 SIRT7 |
| gptkbp:influence |
Gene expression
Aging Metabolism Stress resistance |
| gptkbp:influenced |
Environmental factors
Exercise Dietary compounds Circadian_rhythms |
| gptkbp:is_available_in |
Animals
Bacteria Plants Eukaryotic cells |
| gptkbp:is_governed_by |
Nutritional status
|
| gptkbp:is_involved_in |
Apoptosis
Immune response Metabolic disorders DNA repair Cellular senescence Cellular signaling pathways Neuroprotection Cellular homeostasis Cellular differentiation Cellular repair mechanisms Cellular adaptation Stem cell regulation |
| gptkbp:is_linked_to |
Cardiovascular health
Inflammation Obesity Neurodegenerative diseases Chronic diseases Type 2 diabetes Metabolic health |
| gptkbp:is_studied_in |
Cancer research
Pharmacological agents Cognitive function Potential therapeutic targets Anti-aging therapies Therapeutic_interventions Biomarker_development |
| gptkbp:requires |
gptkb:NAD+
|