Statements (51)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:drug
|
gptkbp:bfsLayer |
6
|
gptkbp:bfsParent |
gptkb:Serono
|
gptkbp:activities |
recombinant human growth hormone
|
gptkbp:approves |
gptkb:FDA
sterile water for injection |
gptkbp:brand |
gptkb:Serostim
|
gptkbp:clinical_trial |
Phase 3
weight gain improve exercise capacity muscle mass increase |
gptkbp:contraindication |
gptkb:Company
active malignancy severe obesity |
gptkbp:dosage_form |
daily
lyophilized powder for reconstitution |
gptkbp:duration |
varies by patient
|
gptkbp:formulation |
powder for injection
|
https://www.w3.org/2000/01/rdf-schema#label |
Serostim
|
gptkbp:indication |
growth hormone deficiency
cachexia |
gptkbp:ingredients |
somatropin
|
gptkbp:interacts_with |
glucocorticoids
estrogens antidiabetic medications |
gptkbp:is_monitored_by |
blood glucose levels
thyroid function tests growth hormone levels |
gptkbp:is_used_for |
HIV-associated wasting syndrome
|
gptkbp:manager |
subcutaneous injection
|
gptkbp:manufacturer |
EMCURE Pharmaceuticals
|
gptkbp:marketed_as |
gptkb:legislation
gptkb:United_States gptkb:Native_American_tribe |
gptkbp:packaging |
vial
|
gptkbp:pharmacokinetics |
excreted in urine
subcutaneous absorption metabolized in liver |
gptkbp:population |
gptkb:Person
adults |
gptkbp:previous_name |
somatropin
|
gptkbp:requires |
prescription only
|
gptkbp:side_effect |
muscle pain
increased cholesterol levels joint pain hypothyroidism injection site reactions carpal tunnel syndrome edema hyperglycemia |
gptkbp:storage |
refrigerated
|